PDRN is short for polydeoxyribonucleotide. These are DNA fragments used in skincare and aesthetic treatments for their potential to support the skin’s renewal processes. The ingredient has become particularly popular thanks to Korean beauty, where it is often associated with skincare aimed at improving the skin’s quality, elasticity and appearance.
PDRN is most commonly derived from DNA purified from salmon cells, although other sources are also used. In skincare formulations, it is used to support skin regeneration, improve hydration and promote a smoother, more elastic-looking complexion. Although it is often described as an ingredient that helps renew the skin, it’s important to distinguish cosmetic products containing PDRN from professional treatments that use it in a different way, as their effects and results cannot be considered equivalent.